Molecular Characterization of Staphylococcus aureus Isolated from Chronic Infected Wounds in Rural Ghana.

ABSTRACT:

Background

Globally, Staphylococcus aureus is an important bacterial pathogen causing a wide range of community and hospital acquired infections. In Ghana, resistance of S. aureus to locally available antibiotics is increasing but the molecular basis of resistance and the population structure of S. aureus in particular in chronic wounds are poorly described. However, this information is essential to understand the underlying mechanisms of resistance and spread of resistant clones. We therefore subjected 28 S. aureus isolates from chronic infected wounds in a rural area of Ghana to whole genome sequencing.

Results

Overall, resistance of S. aureus to locally available antibiotics was high and 29% were Methicillin resistant Staphylococcus a

SUBMITTER: Wolters M 

PROVIDER: S-EPMC7767444 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature