Patterns of β-blocker initiation in patients undergoing intermediate to high-risk noncardiac surgery.

ABSTRACT:

Background

Based on 2 small randomized controlled trials (RCTs) from the 1990s, β-blockers were promoted to prevent perioperative cardiac events in patients undergoing noncardiac surgery. In 2008, a large RCT (POISE trial) showed an increased mortality risk associated with perioperative β-blockade, raising concerns about an extensive β-Blocker use.

Objectives

The objective of the study is to examine patterns of β-Blocker initiation among patients undergoing noncardiac elective surgery in the US.

Methods

From a large, nationwide US health care insurer, we identified patients ≥18 years old who underwent moderate- to high-risk noncardiac elective surgery between 2003 and 2012 and initiated a β-Blocker within 30 days before surgery. We evaluated temporal trends and assess

SUBMITTER: Patorno E 

PROVIDER: S-EPMC7810354 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature