Child outcomes after amnioinfusion compared with no intervention in women with second-trimester rupture of membranes: a long-term follow-up study of the PROMEXIL-III trial.

ABSTRACT:

Objective

To assess the effect of transabdominal amnioinfusion or no intervention on long-term outcomes in children born after second-trimester prelabour rupture of the membranes (PROM between 16^+0/7 -24^+0/7  weeks) and oligohydramnios.

Population

Follow up of infants of women who participated in the randomised controlled trial: PPROMEXIL-III (NTR3492).

Methods

Surviving infants were invited for neurodevelopmental assessment up to 5 years of corrected age using a Bayley Scales of Infant and Toddler Development or a Wechsler Preschool and Primary Scale of Intelligence. Parents were asked to complete several questionnaires.

Main outcome measures

Neurodevelopmental outcomes were measured. Mild delay was defined as -1 standard deviation (SD),

SUBMITTER: de Ruigh AA 

PROVIDER: S-EPMC7818451 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature