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Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index.

ABSTRACT: Irritability is an impairing problem in children with ASD that may be associated with other behavioral and emotional concerns. The Affective Reactivity Index (ARI) is a parent-rated measure of irritability widely used in children with mood disorders, however, its utility in children with ASD remains unclear. In this study, we examined ARI parent ratings in children with ASD and contributions of parent-rated anxiety and noncompliance to irritability measured by the ARI. Participants included 81 children with ASD, aged 8-16 years. Results suggest that both anxiety and noncompliance contribute to irritability, but that anxiety only contributes to irritability in the absence of noncompliance. Further, the ARI is likely to be a useful measure of irritability in children with ASD.

SUBMITTER: Kalvin CB

PROVIDER: S-EPMC7855357 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature

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Assessing Irritability in Children with Autism Spectrum Disorder Using the Affective Reactivity Index.

Kalvin Carla B CB Gladstone Theresa R TR Jordan Rebecca R Rowley Sonia S Marsh Carolyn L CL Ibrahim Karim K Sukhodolsky Denis G DG

Journal of autism and developmental disorders 20210501 5

Irritability is an impairing problem in children with ASD that may be associated with other behavioral and emotional concerns. The Affective Reactivity Index (ARI) is a parent-rated measure of irritability widely used in children with mood disorders, however, its utility in children with ASD remains unclear. In this study, we examined ARI parent ratings in children with ASD and contributions of parent-rated anxiety and noncompliance to irritability measured by the ARI. Participants included 81 c ...[more]

PMID: 32734421

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The Affective Reactivity Index: a concise irritability scale for clinical and research settings.

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Irritability in boys with autism spectrum disorders: an investigation of physiological reactivity.

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The Clinician Affective Reactivity Index: Validity and Reliability of a Clinician-Rated Assessment of Irritability.

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Gene expression in blood of children with autism spectrum disorder

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Measurement and correlates of irritability in clinically referred youth: Further examination of the Affective Reactivity Index.

Project description:BackgroundResearch on youth irritability has proliferated in recent years, largely facilitated by items from existing measures and by key new instruments like the Affective Reactivity Index (ARI). The present study extends this literature by investigating the psychometric properties of the parent- and youth-report ARI and the correlates of irritability in an independent, clinically referred sample.MethodBaseline assessment data were collected from 237 youths (ages 3-18; 36% female) and their parents, seen for outpatient therapy and/or assessment. We examined the ARI in terms of (1) its item, scale, and factor properties; (2) convergent/discriminant validity with internalizing, externalizing, and emotion regulation problems; (3) specificity of associations with reactive aggression, anger, dysregulation, and coping; and (4) robustness of associations after controlling for demographic variables (e.g., age, gender).ResultsThe ARI's internal consistency and unidimensional factor structure were acceptable or better, with some variation across items and informants. Irritability, as measured by parent- and youth-report, was associated with variables in the externalizing (inattention, hyperactivity, executive dysfunction, aggression), internalizing (anxiety, depression, suicidality), and emotion regulation domains. Associations with reactive aggression, anger, dysregulation, and coping problems were especially pronounced. Irritability's links with internalizing and externalizing problems remained robust after controlling for demographic covariates.LimitationsThe sample was limited in diversity and moderate in size.ConclusionsFindings support the reliability and validity of the ARI for assessing parent- and youth-rated irritability among clinically referred youth. Future research is needed to understand variations in irritability's manifestations, measurement, and correlates across demographic groups.

| S-EPMC7954902 | biostudies-literature

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Assessing the Accuracy of the Modified Chinese Autism Spectrum Rating Scale and Social Responsiveness Scale for Screening Autism Spectrum Disorder in Chinese Children.

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