Robotic pancreaticoduodenectomy provides better histopathological outcomes as compared to its open counterpart: a meta-analysis.

ABSTRACT: The aim of this meta-analysis was to evaluate whether robotic pancreaticoduodenectomy (PD) may provide better clinical and pathologic outcomes compared to its open counterpart. The Pubmed, EMBASE, and Cochrane Library were systematically searched. Overall postoperative morbidity and resection margin involvement rate were the primary endpoints. Secondary endpoints included operating time, estimated blood loss (EBL), incisional surgical site infection (SSI) rate, length of hospital stay (LOS), and number of lymph nodes harvested. Twenty-four studies totaling 12,579 patients (2,175 robotic PD and 10,404 open PD were included. Overall postoperative mortality did not significantly differ [OR (95%CI)?=?0.86 (0.74, 1.01); p?=?0.06]. Resection margin involvement rate was significantly lower in robotic PD [15.6% vs. 19.9%; OR (95%CI)?=?0.64 (0.41, 1.00); p?=?0.05; NNT?=?23]. Operating time was significantly longer in robotic PD [MD (95%CI)?=?75.17 (48.05, 102.28); p?

SUBMITTER: Da Dong X 

PROVIDER: S-EPMC7881190 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature