Ontology highlight
ABSTRACT:
SUBMITTER: Ryzhkova A
PROVIDER: S-EPMC7904930 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20210224 1
Generation of mature red blood cells, consisting mainly of hemoglobin, is a remarkable example of coordinated action of various signaling networks. Chromatin condensation is an essential step for terminal erythroid differentiation and subsequent nuclear expulsion in mammals. Here, we profiled 3D genome organization in the blood cells from ten species belonging to different vertebrate classes. Our analysis of contact maps revealed a striking absence of such 3D interaction patterns as loops or TAD ...[more]