Association of glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS): a cross-sectional study.

ABSTRACT:

Background

While survival of systemic lupus erythematosus (SLE) patients has improved substantially, problems remain in the management of their emotional health. Medium to high-dose glucocorticoid doses are known to worsen emotional health; the effect is unclear among patients receiving relatively low-dose glucocorticoids. This study aims to investigate the association between low glucocorticoid doses and emotional health in lupus low disease activity state (LLDAS).

Methods

This cross-sectional study drew on data from SLE patients in 10 Japanese institutions. The participants were adult patients with SLE duration of ≥ 1 year who met LLDAS criteria at the study visit from April 2018 through September 2019. The exposure was the daily glucocorticoid dose (mg oral prednisolone).

SUBMITTER: Miyawaki Y 

PROVIDER: S-EPMC7944592 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature