The effectiveness of vitamin C for patients with severe viral pneumonia in respiratory failure.

ABSTRACT:

Background

Vitamin C is a well-known antioxidant and essential cofactor for numerous biological reactions. Several studies reported that vitamin C can improve the symptoms and prognosis of patients with sepsis and respiratory infection. We aimed to examine the effect of vitamin C when used in viral pneumonia patients with severe respiratory failure.

Methods

Total 201 patients with viral pneumonia were included, of them 35 patients used vitamin C. We performed a statistical analysis through a propensity score matching of the age and baseline characteristics of these patients.

Results

There were differences between the vitamin C group and non-vitamin C group in terms of age (60±15 vs. 66±14, P=0.03), extracorporeal membrane oxygenation (28.6% vs. 5.4%, P<0

SUBMITTER: Lee SI 

PROVIDER: S-EPMC7947518 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature