Dataset Information

Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.

ABSTRACT:

Introduction

The SARS-CoV-2 pandemic presented healthcare providers with an extreme challenge to provide cancer services. The impact upon the diagnostic and treatment capacity to treat pancreatic cancer is unclear. This study aimed to identify national variation in treatment pathways during the pandemic.

Methods

A survey was distributed to all United Kingdom pancreatic specialist centres, to assess diagnostic, therapeutic and interventional services availability, and alterations in treatment pathways. A repeating methodology enabled assessment over time as the pandemic evolved.

Results

Responses were received from all 29 centres. Over the first six weeks of the pandemic, less than a quarter of centres had normal availability of diagnostic pathways and a fifth of centres had no capacity whatsoever to undertake surgery. As the pandemic progressed services have gradually improved though most centres remain constrained to some degree. One third of centres changed their standard resectable pathway from surgery-first to neoadjuvant chemotherapy. Elderly patients, and those with COPD were less likely to be offered treatment during the pandemic.

Conclusion

The COVID-19 pandemic has affected the capacity of the NHS to provide diagnostic and staging investigations for pancreatic cancer. The impact of revised treatment pathways has yet to be realised.

SUBMITTER: McKay SC

PROVIDER: S-EPMC7973054 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Publications

Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.

McKay Siobhan C SC Pathak Samir S Wilkin Richard J W RJW Kamarajah Sivesh K SK Wigmore Stephen J SJ Rees Jonathan J Dunne Declan F J DFJ Garcea Giuseppe G Ahmad Jawad J de Liguori Carino Nicola N Sultana Asma A Silva Mike M Lykoudis Pavlos P Nasralla David D Milburn James J Shah Nehal N Kocher Hemant M HM Bhogal Ricky R Baron Ryan D RD Navarro Alex A Halle-Smith James J Al-Sarireh Bilal B Sen Gourab G Jamieson Nigel B NB Briggs Christopher C Stell David D Aroori Somaiah S Bowles Matthew M Kanwar Aditya A Harper Simon S Menon Krishna K Prachalias Andreas A Srinivasan Parthi P Frampton Adam E AE Jones Claire C Arshad Ali A Tait Iain I Spalding Duncan D Young Alastair L AL Durkin Damien D Ghods-Ghorbani Manijeh M Sutcliffe Robert P RP Roberts Keith J KJ

HPB : the official journal of the International Hepato Pancreato Biliary Association 20210319 11

<h4>Introduction</h4>The SARS-CoV-2 pandemic presented healthcare providers with an extreme challenge to provide cancer services. The impact upon the diagnostic and treatment capacity to treat pancreatic cancer is unclear. This study aimed to identify national variation in treatment pathways during the pandemic.<h4>Methods</h4>A survey was distributed to all United Kingdom pancreatic specialist centres, to assess diagnostic, therapeutic and interventional services availability, and alterations i ...[more]

PMID: 34544628

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Project description:IntroductionPrenatal mental health problems are associated with morbidity for the pregnant person, and their infants are at long-term risk for poor health outcomes. We aim to explore how the SARS-CoV-2 pandemic affected the mental health of pregnant people in the United Kingdom (UK), and to further identify resilience factors which may have contributed to varying mental health outcomes. We also aim to examine the quality of antenatal care provided during the pandemic in the UK and to identify potential inadequacies to enhance preparedness for future events.MethodsDuring June-November 2020, we recruited 3666 individuals in the UK for the EPPOCH pregnancy cohort (Maternal mental health during the COVID-19 pandemic: Effect of the Pandemic on Pregnancy Outcomes and Childhood Health). Participants were assessed for depression, anxiety, anger and pregnancy-related anxiety using validated scales. Additionally, physical activity, social support, individualized support and personal coping ability of the respondents were assessed as potential resilience factors.ResultsParticipants reported high levels of depression (57.05%), anxiety (58.04%) and anger (58.05%). Higher levels of social and individualized support and personal coping ability were associated with lower mental health challenges. Additionally, pregnant individuals in the UK experienced higher depression during the pandemic than that reported in Canada. Finally, qualitative analysis revealed that restrictions for partners and support persons during medical appointments as well as poor public health communication led to increased mental health adversities and hindered ability to make medical decisions.DiscussionThis study revealed increased mental health challenges among pregnant individuals in the UK during the SARS-CoV-2 pandemic. These results highlight the need for reassessing the mental health support measures available to pregnant people in the UK, both during times of crisis and in general.

Dataset Information

Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.

Introduction

Methods

Results

Conclusion

Publications

Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience.

Similar Datasets

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