Brain activation patterns in medicated versus medication-naive adults with attention-deficit hyperactivity disorder during fMRI tasks of motor inhibition and cognitive switching.

ABSTRACT:

Background

Adult-attention-deficit-hyperactive-disorder (ADHD) is often unrecognized condition. FMRI examination along with neuropsychological testing might strengthen the diagnosis. We hypothesized that ADHD-adults with and without medication would show different fMRI pattern compared to healthy controls while testing tasks of motor inhibition and cognitive switching.

Methods

45 subjects in three age-matched groups: (1) controls, (2) ADHD-adults under medication (ADHD+) and (3) medication-naïve adults with ADHD (ADHD-) underwent fMRI and neuropsychological testing. Group analysis and population-based statistics were performed.

Results

DTVP-A, intellectual ability as well as attention capability, visual-perceptual and visual-motor abilities showed no significant diffe

SUBMITTER: Berberat J 

PROVIDER: S-EPMC7977301 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature