Biocatalytic Reduction Reactions from a Chemist's Perspective.

ABSTRACT: Reductions play a key role in organic synthesis, producing chiral products with new functionalities. Enzymes can catalyse such reactions with exquisite stereo-, regio- and chemoselectivity, leading the way to alternative shorter classical synthetic routes towards not only high-added-value compounds but also bulk chemicals. In this review we describe the synthetic state-of-the-art and potential of enzymes that catalyse reductions, ranging from carbonyl, enone and aromatic reductions to reductive aminations.

SUBMITTER: Hollmann F 

PROVIDER: S-EPMC7983917 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature