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Structural insights into SARS-CoV-2 infection and therapeutics development.

ABSTRACT: The current COVID-19 pandemic is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). By late October 2020, more than 43 million cases of infections, including over 1.15 million deaths, have been confirmed worldwide. This review focuses on our current understanding of SARS-CoV-2 from the perspective of the three-dimensional (3D) structures of SARS-CoV-2 viral proteins and their implications on therapeutics development against COVID-19.

SUBMITTER: Sun G 

PROVIDER: S-EPMC7985237 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Structural insights into SARS-CoV-2 infection and therapeutics development.

Sun Gangyu G   Xue Lulu L   He Qingjing Q   Zhao Yue Y   Xu Wenqing W   Wang Zhizhi Z  

Stem cell research 20210202

The current COVID-19 pandemic is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). By late October 2020, more than 43 million cases of infections, including over 1.15 million deaths, have been confirmed worldwide. This review focuses on our current understanding of SARS-CoV-2 from the perspective of the three-dimensional (3D) structures of SARS-CoV-2 viral proteins and their implications on therapeutics development against COVID-19. ...[more]