Short term associations of ambient nitrogen dioxide with daily total, cardiovascular, and respiratory mortality: multilocation analysis in 398 cities.

ABSTRACT:

Objective

To evaluate the short term associations between nitrogen dioxide (NO₂) and total, cardiovascular, and respiratory mortality across multiple countries/regions worldwide, using a uniform analytical protocol.

Design

Two stage, time series approach, with overdispersed generalised linear models and multilevel meta-analysis.

Setting

398 cities in 22 low to high income countries/regions.

Main outcome measures

Daily deaths from total (62.8 million), cardiovascular (19.7 million), and respiratory (5.5 million) causes between 1973 and 2018.

Results

On average, a 10 μg/m³ increase in NO₂ concentration on lag 1 day (previous day) was associated with 0.46% (95% confidence interval 0.36% to 0.57%), 0.37% (0.22% to 0.51%), and

SUBMITTER: Meng X 

PROVIDER: S-EPMC7988454 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature