Is Ovarian Reserve Impacted in Anorexia Nervosa?

ABSTRACT:

Study objectives

Hypothalamic amenorrhea is common in adolescents and young adults (AYAs) with anorexia nervosa (AN), and ovarian reserve is not routinely assessed. AN increases rates of fertility problems, but how or when AN negatively influences future fertility is unclear. We sought to determine whether biomarkers of ovarian reserve were impacted in AYA with AN.

Design

Cross-sectional study.

Setting

Tertiary care center.

Participants

Females with AN and amenorrhea (n = 97) at the pre-intervention visit of a clinical trial, n = 19 females without an eating disorder or menstrual dysfunction.

Main outcome measures

Serum anti-Müllerian hormone (AMH) concentrations.

Results

AMH levels were higher in AYA with AN than unaffected adolescents (4.7 vs. 3

SUBMITTER: Pitts S 

PROVIDER: S-EPMC8005478 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature