Novel Fluorescent Probe toward Fe³⁺ Based on Rhodamine 6G Derivatives and Its Bioimaging in Adult Mice, Caenorhabditis elegans, and Plant Tissues.

ABSTRACT: A new fluorescent probe LXY based on the rhodamine 6G platforms has been designed, synthesized, and characterized, which could recognize Fe³⁺ effectively in HEPES buffer (10 mM, pH = 7.4)/CH₃CN (2:3, v/v). And the distinct color change and the rapid emergence of fluorescence emission at 550 nm achieved "naked eye" detection of Fe³⁺. The interaction mode between them was achieved by Job's plot, MS, SEM, and X-ray single-crystal diffraction. Importantly, the crystal structures proved that Fe³⁺ could induce the rhodamine moiety transform the closed-cycle form to the open-cycle form. But it is interesting that Fe³⁺ did not appear in the crystal structures. Meanwhile, the limit of detection (LOD) of LXY to Fe³⁺ was

SUBMITTER: Zhang J 

PROVIDER: S-EPMC8015108 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature