Taxon-Specific Proteins of the Pathogenic Entamoeba Species E. histolytica and E. nuttalli.

ABSTRACT: The human protozoan parasite Entamoeba histolytica can live in the human intestine for months or years without generating any symptoms in the host. For unknown reasons, amoebae can suddenly destroy the intestinal mucosa and become invasive. This can lead to amoebic colitis or extraintestinal amoebiasis whereby the amoebae spread to other organs via the blood vessels, most commonly the liver where abscesses develop. Entamoeba nuttalli is the closest genetic relative of E. histolytica and is found in wild macaques. Another close relative is E. dispar, which asyptomatically infects the human intestine. Although all three species are closely related, only E. histolytica and E. nuttalli are able to penetrate their host's intestinal epithelium. Li

SUBMITTER: Konig C 

PROVIDER: S-EPMC8017271 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature