Different positron emission tomography findings in schizophrenia and narcolepsy type 1 in adolescents and young adults: a preliminary study.

ABSTRACT:

Study objectives

The association between schizophrenia and narcolepsy has been controversial. We conducted a prospective case control study of schizophrenia and comorbid narcolepsy type 1 in adolescents compared with patients with either diagnosis alone and healthy controls using ¹⁸F-fluorodeoxy glucose positron emission tomography, sleep studies, and neurocognitive tests.

Methods

We included 11 patients (9-20 years old) with schizophrenia and comorbid narcolepsy type 1, 11 with narcolepsy type 1, 11 with schizophrenia, and 11 controls. All groups were matched for age and sex. Participants were required to submit to clinical interviews for sleep and psychiatric disorders, sleep questionnaires, continuous performance test, Wisconsin card sorting test, sleep studies

SUBMITTER: Chin WC 

PROVIDER: S-EPMC8020687 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature