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The efficacy of N-Acetylcysteine in severe COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial.

ABSTRACT:

SUBMITTER: Rahimi A

PROVIDER: S-EPMC8040363 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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The efficacy of N-Acetylcysteine in severe COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial.

Rahimi Arash A Samimagham Hamid Reza HR Azad Mehdi Hassani MH Hooshyar Dariush D Arabi Mohsen M KazemiJahromi Mitra M

Trials 20210412 1

<h4>Objectives</h4>Severe acute respiratory infection (SARI) caused by the SARS-CoV-2 virus may cause lung failure and the need for mechanical ventilation. Infection with SARS-COV-2 can lead to activation of inflammatory factors, increased reactive oxygen species, and cell damage. In addition to mucolytic effects, N-Acetylcysteine has antioxidant effects that we believe can help patients recover. In this study, we evaluate the efficacy of N-Acetylcysteine in patients with severe COVID-19.<h4>Tri ...[more]

PMID: 33845881

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Dataset Information

The efficacy of N-Acetylcysteine in severe COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial.

Publications

The efficacy of N-Acetylcysteine in severe COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial.

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