Dataset Information

Association Between Preeclampsia Risk and Fine Air Pollutants and Acidic Gases: A Cohort Analysis in Taiwan.

ABSTRACT: Background: Fine air pollutant particles have been reported to be associated with risk of preeclampsia. The association between air pollutant exposure and preeclampsia risk in heavily air polluted Taiwan warrants investigation. Methods: We combined data from Taiwan National Health Insurance (NHI) Research Database (NHIRD) and Taiwan Air Quality Monitoring Database. Women aged 16-55 years were followed from January 1, 2000, until appearance of ICD-9 coding of preeclampsia withdrawal from the NHI program, or December 31, 2013. Daily concentration of NOx, NO, NO₂, and CO was calculated by Kriging method. The Cox proportional hazard regression model was used for risk assessment. Results: For NOx, Relative to Quartile [Q] 1 concentrations, the Q2 (adjusted hazard ratio adjusted = 2.20, 95% CI = 1.50-3.22), Q3 (aHR = 7.28, 95% CI = 4.78-11.0), and Q4 (aHR = 23.7, 95% CI = 13.7-41.1) concentrations were associated with a significantly higher preeclampsia or eclampsia risk. Similarly, for NO, relative to Q1 concentrations, the Q2 (aHR = 1.82, 95% CI = 1.26-2.63), Q3 (aHR = 7.53, 95% CI = 5.12-11.0), and Q4 (aHR = 11.1, 95% CI = 6.72-18.3) concentrations were correlated with significantly higher preeclampsia or eclampsia risk. Furthermore, for NO₂, relative to Q1 concentration, the Q2 (aHR = 1.99, 95% CI = 1.37-2.90), Q3 (aHR = 6.15, 95% CI = 3.95-9.57), and Q4 (aHR = 32.7, 95% CI = 19.7-54.3) concentrations also associated with a significantly higher preeclampsia or eclampsia risk. Conclusion: Women exposed to higher NO_X, NO, NO₂, and CO concentrations demonstrated higher preeclampsia incidence.

SUBMITTER: Lin SY

PROVIDER: S-EPMC8044398 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Publications

Association Between Preeclampsia Risk and Fine Air Pollutants and Acidic Gases: A Cohort Analysis in Taiwan.

Lin Shih-Yi SY Yang Yu-Cih YC Su Jun-Wei JW Wang Jie-Sian JS Jiang Chang-Cheng CC Hsu Chung-Y CY Kao Chia-Hung CH

Frontiers in public health 20210331

<b>Background:</b> Fine air pollutant particles have been reported to be associated with risk of preeclampsia. The association between air pollutant exposure and preeclampsia risk in heavily air polluted Taiwan warrants investigation. <b>Methods:</b> We combined data from Taiwan National Health Insurance (NHI) Research Database (NHIRD) and Taiwan Air Quality Monitoring Database. Women aged 16-55 years were followed from January 1, 2000, until appearance of ICD-9 coding of preeclampsia withdrawal ...[more]

PMID: 33869125

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Project description:BackgroundAir pollution in China has raised great concerns due to its adverse effects on air quality, human health, and climate. Emissions of air pollutants (APs) are inherently linked with CO2 emissions through fossil-energy consumption. Knowledge of the characteristics of APs and CO2 emissions and their relationships is fundamentally important in the pursuit of co-benefits in addressing air quality and climate issues in China. However, the linkages and interactions between APs and CO2 in China are not well understood.ResultsHere, we conducted an ensemble study of six bottom-up inventories to identify the underlying drivers of APs and CO2 emissions growth and to explore their linkages in China. The results showed that, during 1980-2015, the power and industry sectors contributed 61-79% to China's overall emissions of CO2, NOx, and SO2. In addition, the residential and industrial sectors were large emitters (77-85%) of PM10, PM2.5, CO, BC, and OC. The emissions of CH4, N2O and NH3 were dominated by the agriculture sector (46-82%) during 1980-2015, while the share of CH4 emissions in the energy sector increased since 2010. During 1980-2015, APs and greenhouse gases (GHGs) emissions from residential sources generally decreased over time, while the transportation sector increased its impact on recent emissions, particularly for NOx and NMVOC. Since implementation of stringent pollution control measures and accompanying technological improvements in 2013, China has effectively limited pollution emissions (e.g., growth rates of -10% per year for PM and -20% for SO2) and slowed down the increasing trend of carbon emissions from the power and industrial sectors. We also found that areas with high emissions of CO, NOx, NMVOC, and SO2 also emitted large amounts of CO2, which demonstrates the possible common sources of APs and GHGs. Moreover, we found significant correlations between CO2 and APs (e.g., NOx, CO, SO2, and PM) emissions in the top 5% high-emitting grid cells, with more than 60% common grid cells during 2010-2015.ConclusionsWe found significant correlation in spatial and temporal aspects for CO2, and NOx, CO, SO2, and PM emissions in China. We targeted sectorial and spatial APs and GHGs emission hot-spots, which help for management and policy-making of collaborative reductions of them. This comprehensive analysis over 6 datasets improves our understanding of APs and GHGs emissions in China during the period of rapid industrialization from 1980 to 2015. This study helps elucidate the linkages between APs and CO2 from an integrated perspective, and provides insights for future synergistic emissions reduction.

Dataset Information

Association Between Preeclampsia Risk and Fine Air Pollutants and Acidic Gases: A Cohort Analysis in Taiwan.

Publications

Association Between Preeclampsia Risk and Fine Air Pollutants and Acidic Gases: A Cohort Analysis in Taiwan.

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