Ontology highlight
ABSTRACT:
SUBMITTER: Dilweg IW
PROVIDER: S-EPMC8078501 | biostudies-literature | 2021 May
REPOSITORIES: biostudies-literature
Dilweg Ivar W IW Bouabda Assia A Dalebout Tim T Gultyaev Alexander P AP Bredenbeek Peter J PJ Olsthoorn R C L RCL
RNA biology 20201016 5
Subgenomic RNAs are produced by several RNA viruses through incomplete degradation of their genomic RNA by the exoribonuclease Xrn1, and have been shown to be essential for viral growth and pathogenicity. Within the flavivirus genus of the <i>Flaviviridae</i> family, two distinct classes of Xrn1-resistant RNA motifs have been proposed; one for mosquito-borne and insect-specific flaviviruses, and one for tick-borne flaviviruses and no-known-vector flaviviruses. We investigated tick-borne and no-k ...[more]