Prenatal metal mixtures and fetal size in mid-pregnancy in the MADRES study.

ABSTRACT:

Background

Fetal growth is predictive of health later in life. Both toxic and essential metals influence fetal growth, but most studies have focused on these elements individually and used birth weight as an indicator of fetal growth. The objective of the current study was to investigate the impact of a mixture of metals on fetal size in mid-pregnancy in a predominately lower income Hispanic pregnancy cohort in Los Angeles.

Methods

For our primary analysis, we focused on six elements that have previously been associated individually with fetal size, including arsenic (As), barium (Ba), cadmium (Cd), mercury (Hg), molybdenum (Mo), and tin (Sn), measured in maternal urine samples collected in early pregnancy (median: 12.4 weeks gestation). In an exploratory analysis, we additi

SUBMITTER: Howe CG 

PROVIDER: S-EPMC8079562 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature