The effect of different measurement modalities in the association of lean mass with mortality: A systematic review and meta-analysis.

ABSTRACT:

Objectives

Lean mass is commonly measured by 3 modalities, dual energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), and computerized tomography (CT). CT is considered the most accurate, while lean mass measured by DXA and BIA often consists of non-muscle compartment, and hence considered less accurate when compared with CT. It remains unclear if the association of lean mass with mortality would differ using different measurement modalities.

Methods

A systematic review and meta-analysis of lean mass and mortality was conducted. The analysis was stratified by different measurement modalities and health conditions. Pooled hazard ratios were estimated using a random effects model.

Results

This meta-analysis included 188 studies with 98 468 participa

SUBMITTER: Li GH 

PROVIDER: S-EPMC8088995 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature