Novel mapping techniques for rotor core detection using simulated intracardiac electrograms.

ABSTRACT:

Background

Catheter ablation is associated with limited success rates in patients with persistent atrial fibrillation (AF). Currently, existing mapping systems fail to identify critical target sites for ablation. Recently, we proposed and validated several techniques (multiscale frequency [MSF], Shannon entropy [SE], kurtosis [Kt], and multiscale entropy [MSE]) to identify pivot point of rotors using ex-vivo optical mapping animal experiments. However, the performance of these techniques is unclear for the clinically recorded intracardiac electrograms (EGMs), due to the different nature of the signals.

Objective

This study aims to evaluate the performance of MSF, MSE, SE, and Kt techniques to identify the pivot point of the rotor using unipolar and bipolar EGMs obtained from

SUBMITTER: Ravikumar V 

PROVIDER: S-EPMC8119376 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature