Direct Diagnosis of Echovirus 12 Meningitis Using Metagenomic Next Generation Sequencing.

ABSTRACT: The current point-of-care diagnosis of enterovirus meningitis does not identify the viral genotype, which is prognostic. In this case report, more than 81% of an Echovirus 12 genome were detected and identified by metagenomic next-generation sequencing, directly from the cerebrospinal fluid collected in a 6-month-old child with meningeal syndrome and meningitis: introducing Echovirus 12 as an etiological agent of acute meningitis in the pediatric population.

SUBMITTER: Morsli M 

PROVIDER: S-EPMC8156364 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature