The Role of Multisystem Disease in Composition of Autologous Serum tears and ocular surface symptom improvement.

ABSTRACT:

Purpose

Autologous serum tears (AST) contain growth factors and vitamins similar to those in healthy tears and are an effective treatment option for ocular surface disease. This study determined the differences in composition of AST in patients with systemic diseases versus patients with localized ocular surface diseases and the effects on ocular surface symptom improvement.

Method

An observational study was performed on 53 patients with either systemic diseases (Group I) or localized ocular surface diseases (Group II) who were prescribed AST. Concentrations of epidermal growth factor (EGF), interleukin 8 (IL-8), fibronectin, vitamin A, and tumor necrosis factor-α (TNF-α) were determined through ELISA assays from patients in both groups. The Ocular Surface Disease Index (OSD

SUBMITTER: Ripa M 

PROVIDER: S-EPMC8207622 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature