Learning Optimal Distributionally Robust Individualized Treatment Rules.

ABSTRACT: Recent development in the data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, policy makers best individualized treatment rule (ITR) that maximizes the expected outcome, known as the value function. Many existing methods assume that the training and testing distributions are the same. However, the estimated optimal ITR may have poor generalizability when the training and testing distributions are not identical. In this paper, we consider the problem of finding an optimal ITR from a restricted ITR class where there is some unknown covariate changes between the training and testing distributions. We propose a novel distributionally robust ITR (DR-ITR) framework that maximizes the wo

SUBMITTER: Mo W 

PROVIDER: S-EPMC8221611 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature