Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data.

ABSTRACT:

Background

Greater subjective cognitive changes on the Cognitive Function Index (CFI) was previously found to be associated with elevated amyloid (Aß) status in participants screening for the A4 Study, reported by study partners and the participants themselves. While the total score on the CFI related to amyloid for both sources respectively, potential differences in the specific types of cognitive changes reported by either participants or their study partners was not investigated.

Objectives

To determine the specific types of subjective cognitive changes endorsed by participants and their study partners that are associated with amyloid status in individuals screening for an AD prevention trial.

Design, setting, participants

Four thousand four hundred and eighty-six

SUBMITTER: Amariglio RE 

PROVIDER: S-EPMC8240963 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature