Dataset Information

Comparison of Multimodal Therapies and Outcomes Among Patients With High-Risk Prostate Cancer With Adverse Clinicopathologic Features.

ABSTRACT:

Importance

The optimal management strategy for high-risk prostate cancer and additional adverse clinicopathologic features remains unknown.

Objective

To compare clinical outcomes among patients with high-risk prostate cancer after definitive treatment.

Design, setting, and participants

This retrospective cohort study included patients with high-risk prostate cancer (as defined by the National Comprehensive Cancer Network [NCCN]) and at least 1 adverse clinicopathologic feature (defined as any primary Gleason pattern 5 on biopsy, clinical T3b-4 disease, ≥50% cores with biopsy results positive for prostate cancer, or NCCN ≥2 high-risk features) treated between 2000 and 2014 at 16 tertiary centers. Data were analyzed in November 2020.