Reappraisal of mechanical tricuspid valve replacement in the current era: a single center retrospective study.

ABSTRACT:

Background

This study aimed to investigate the early and late outcomes of mechanical tricuspid valve replacement (mTVR).

Methods

We evaluated 113 patients (82 women; median age, 53 years) who underwent mTVR between 1995 and 2017. Based on a history of cardiac surgery, patients were divided into primary (n=42) and reoperative mTVR (n=71) groups. The median follow-up duration was 12.7 years in primary and 9.3 years in reoperative mTVR, respectively (P=0.045).

Results

Patients in the reoperative group were older (54 vs. 46 years; P=0.007) and showed higher central venous pressure (16±6 vs. 13±6 mmHg; P=0.002) than the primary group. Early mortality occurred in 2 patients in the reoperative group (2 vs. 0; P=0.529). There was no significant difference in overall survival between the primary and reoperation groups (15-year survival rate: 86% vs. 78%; P=0.215). The independent risk factors of overall survival were age [P<0.001; hazard ratio (HR), 1.11; 95% confidential interval (CI), 1.05-1.18], left ventricular ejection fraction of less than 40% (P=0.001; HR, 5.1; 95% CI, 2.21-28.2), and central venous pressure over 20 mmHg (P=0.016; HR, 3.7; 95% CI, 1.28-10.7). Overall survival did not differ between the age groups (<60 vs. 60-70 years) in the reoperative group (P=0.772). Tricuspid valve thrombosis occurred in 8 patients (7 primary, 1 reoperative; P=0.004).

Conclusions

The incidence of tricuspid valve thrombosis was significantly higher in the primary mTVR group compared with the reoperative mTVR group. The patients who underwent mTVR at a relatively young age showed good early and late outcomes in both groups.

SUBMITTER: Park B 

PROVIDER: S-EPMC8264679 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature