Prevalence of and Factors Associated with Sleep-Wake Abnormalities in Patients with Cirrhosis.

ABSTRACT:

Background & aims

Sleep-wake abnormalities [poor nighttime sleep and excessive daytime sleepiness (EDS)] are common in patients with cirrhosis. The aim of this study was to assess the prevalence of sleep-wake abnormalities and clinical factors associated with these abnormalities in a group of patients with cirrhosis.

Methods

1098 patients with cirrhosis [Child Turcotte Pugh (CTP) class A, 22.2%; CTP class B, 29.2% and CTP class C, 48.6%], with either no ascites or mild ascites controlled on diuretics, and no history of or current overt hepatic encephalopathy were included in the study.

Results

Poor nighttime sleep and EDS were found in 569 (51.8%) and 489 (44.5%) patients respectively. On multivariate analysis, factors associated with poor nighttime sleep were CTP cla

SUBMITTER: Kumar M 

PROVIDER: S-EPMC8267360 | biostudies-literature | 2021 Jul-Aug

REPOSITORIES: biostudies-literature