Ontology highlight
ABSTRACT:
SUBMITTER: Rogers MF
PROVIDER: S-EPMC8293831 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Rogers Mark F MF Gaunt Tom R TR Campbell Colin C
Briefings in bioinformatics 20210701 4
Sequencing technologies have led to the identification of many variants in the human genome which could act as disease-drivers. As a consequence, a variety of bioinformatics tools have been proposed for predicting which variants may drive disease, and which may be causatively neutral. After briefly reviewing generic tools, we focus on a subset of these methods specifically geared toward predicting which variants in the human cancer genome may act as enablers of unregulated cell proliferation. We ...[more]