COGENT: evaluating the consistency of gene co-expression networks.
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ABSTRACT: Summary
Gene co-expression networks can be constructed in multiple different ways, both in the use of different measures of co-expression, and in the thresholds applied to the calculated co-expression values, from any given dataset. It is often not clear which co-expression network construction method should be preferred. COGENT provides a set of tools designed to aid the choice of network construction method without the need for any external validation data.Availability and implementation
https://github.com/lbozhilova/COGENT.Supplementary information
Supplementary information is available at Bioinformatics online.
SUBMITTER: Bozhilova LV
PROVIDER: S-EPMC8317122 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
COGENT: evaluating the consistency of gene co-expression networks.
Bozhilova Lyuba V LV Pardo-Diaz Javier J Reinert Gesine G Deane Charlotte M CM
Bioinformatics (Oxford, England) 20210701 13
<h4>Summary</h4>Gene co-expression networks can be constructed in multiple different ways, both in the use of different measures of co-expression, and in the thresholds applied to the calculated co-expression values, from any given dataset. It is often not clear which co-expression network construction method should be preferred. COGENT provides a set of tools designed to aid the choice of network construction method without the need for any external validation data.<h4>Availability and implemen ...[more]
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