A Near-Infrared Light Triggered Composite Nanoplatform for Synergetic Therapy and Multimodal Tumor Imaging.

ABSTRACT: Transition-metal chalcogenide compounds with facile preparation and multifunctional elements act as ideal photothermal agents for cancer theranostics. This work synthesizes Cu_7.2S₄/5MoS₂ composite nanoflowers and investigates the crystal growth mechanism to optimize the synthesis strategy and obtain excellent photothermal therapy agents. Cu_7.2S₄/5MoS₂ exhibits a high photothermal conversion efficiency of 58.7% and acts as a theranostic nanoplatform and demonstrated an effective photothermal-chemodynamic-photodynamic synergetic therapeutic effect in both in vitro and in vivo tests. Moreover, Cu_7.2S₄/5MoS₂ shows strong photoacoustic signal amplitudes and computed tomographic contr

SUBMITTER: Wu M 

PROVIDER: S-EPMC8339317 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature