Dysregulation of microRNA and Intracerebral Hemorrhage: Roles in Neuroinflammation.
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ABSTRACT:
SUBMITTER: Kashif H
PROVIDER: S-EPMC8347974 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
Dysregulation of microRNA and Intracerebral Hemorrhage: Roles in Neuroinflammation.
Kashif Hisham H Shah Dilan D Sukumari-Ramesh Sangeetha S
International journal of molecular sciences 20210729 15
Intracerebral hemorrhage (ICH) is a major public health problem and devastating subtype of stroke with high morbidity and mortality. Notably, there is no effective treatment for ICH. Neuroinflammation, a pathological hallmark of ICH, contributes to both brain injury and repair and hence, it is regarded as a potential target for therapeutic intervention. Recent studies document that microRNAs, small non-coding RNA molecules, can regulate inflammatory brain response after ICH and are viable molecu ...[more]
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