Dorsal vagal nucleus involvement relates to QTc-prolongation after acute medullary infarction.

ABSTRACT:

Background

Infarction of the medulla has been associated with prolongation of the QTc, severe arrhythmia, and sudden cardiac death, yet the precise anatomical substrate remains uncertain.

Aims

We sought to determine the possible anatomical structures relating to QTc-prolongation in patients with acute medullary infarction.

Methods

We included 12 subjects with acute ischemic medullary infarction on brain MRI, who presented within 4.5 h from the last known well time, with a 90-day follow-up. For an unbiased lesion analysis, medullary infarcts were manually outlined on diffusion weighted MRI and co-registered with an anatomical atlas.

Results

Nine out of 12 had QTc-prolongation. Qualitative and semi-quantitative comparisons were made between infarct location and Q

SUBMITTER: Je G 

PROVIDER: S-EPMC8349856 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature