Obesity and metabolic abnormalities as risks of alcoholic fatty liver in men: NAGALA study.

ABSTRACT:

Background

Hepatic steatosis has a pivotal role in the development of chronic liver diseases, even in alcohol-related liver disease. Alcoholic fatty liver disease is an important phenotype among alcohol-related liver diseases. While metabolic syndrome is a dominant risk factor of incident nonalcoholic fatty liver disease, the role of metabolic syndrome in alcoholic fatty liver disease has not been clarified yet.

Methods

A retrospective cohort study was performed at a health check-up center in Japan. Subjects consisted of male participants without fatty liver who consumed ethanol of 420 g/week or higher. Adjusted hazard ratios and 95% confidence intervals at the baseline examinations for incident alcoholic fatty liver disease were estimated using Cox model.

Results

A t

SUBMITTER: Yoshimura Y 

PROVIDER: S-EPMC8353849 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature