Ontology highlight
ABSTRACT:
SUBMITTER: Varuzhanyan G
PROVIDER: S-EPMC8380467 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Varuzhanyan Grigor G Ladinsky Mark S MS Yamashita Shun-Ichi SI Abe Manabu M Sakimura Kenji K Kanki Tomotake T Chan David C DC
Development (Cambridge, England) 20210812 16
Male germline development involves choreographed changes to mitochondrial number, morphology and organization. Mitochondrial reorganization during spermatogenesis was recently shown to require mitochondrial fusion and fission. Mitophagy, the autophagic degradation of mitochondria, is another mechanism for controlling mitochondrial number and physiology, but its role during spermatogenesis is largely unknown. During post-meiotic spermatid development, restructuring of the mitochondrial network re ...[more]