Egyptian Olea europaea leaves bioactive extract: Antibacterial and wound healing activity in normal and diabetic rats.

ABSTRACT:

Background and aim

In vitro activity evaluation of Egyptian Olea europaea leaves extracts, and in vivo healing activity assessment of the newly prepared ointment of Olea europaea leaves extracts mingled with Shea butter.

Experimental procedure

Different extraction methods and solvents were used to extract Egyptian Olea europaea bioactive agent(s). Antibacterial, scavenging activity and in-vivo evaluation of wound repair potentiality of Olea europaea extract were examined in normal and diabetic experimental rat models with induced circular excisions.

Results and conclusion

Olive leaves extract of Tanta was selected as the most active agent against Methicillin-resistant S. aureus (MRSA), with MIC value 15.6 μg/ml.

SUBMITTER: Elnahas RA 

PROVIDER: S-EPMC8427474 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature