Comparison of Skin Antiseptic Agents and the Role of 0.01% Hypochlorous Acid.

ABSTRACT:

Background

Hypochlorous acid (HA) has both anti-microbial and wound-healing properties with a growing role for utilization in pre-procedural care on the face.

Objectives

The authors sought to compare the antiseptic property of 0.01% HA solution, 5% povidone iodine (PI), 4% chlorhexidine gluconate (CHG), and 70% isopropyl alcohol (IPA) antiseptic on facial skin.

Methods

This was a prospective single-center clinical trial.

Results

A total of 21 participants were recruited. Bacterial growth was seen in CHG (10%), IPA (71%), PI (81%), and HA (95%) of specimens (P < 0.001). CHG had less growth compared with HA (P = <0.001), IPA (P = <0.001), and PI (P = <0.001). No difference in bacterial growth was noted between HA and IPA (P = 0.063) or HA and PI (P = 0.25). Signi

SUBMITTER: Tran AQ 

PROVIDER: S-EPMC8438591 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature