Novel 4DCT Method to Measure Regional Left Ventricular Endocardial Shortening Before and After Transcatheter Mitral Valve Implantation.

ABSTRACT:

Background

Regional left ventricular (LV) mechanics in mitral regurgitation (MR) patients, and local changes in function after transcatheter mitral valve implantation (TMVI) have yet to be evaluated. Herein, we introduce a method for creating high resolution maps of endocardial function from 4DCT images, leading to detailed characterization of changes in local LV function. These changes are particularly interesting when evaluating the effect of the Tendyne^™ TMVI device in the region of the epicardial pad.

Methods

Regional endocardial shortening from CT (RS_CT) was evaluated in Tendyne (Abbott Medical) TMVI patients with 4DCT exams pre- and post-implantation. Regional function was evaluated in 90 LV segments (5 longitudinal × 18 circumferential). LV volum

SUBMITTER: Colvert GM 

PROVIDER: S-EPMC8445197 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature