Transcriptomic profile of leg muscle during early growth and development in Haiyang yellow chicken.

ABSTRACT: Skeletal muscle growth and development from embryo to adult consists of a series of carefully regulated changes in gene expression. This study aimed to identify candidate genes involved in chicken growth and development and to investigate the potential regulatory mechanisms of early growth in Haiyang yellow chicken. RNA sequencing was used to compare the transcriptomes of chicken muscle tissues at four developmental stages. In total, 6150 differentially expressed genes (DEGs) ( | fold change |   ≥  2; false discovery rate (FDR)  ≤  0.05) were detected by pairwise comparison in female chickens. Functional analysis showed that the DEGs were mainly involved in the processes of muscle growth and development and cell differentiation. Many of the DEGs, such as MSTN, MYOD1, MYF6<

SUBMITTER: Yin X 

PROVIDER: S-EPMC8461557 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature