Coverage and Estimated Effectiveness of mRNA COVID-19 Vaccines Among US Veterans.

ABSTRACT:

Importance

Effectiveness of mRNA vaccinations in a diverse older population with high comorbidity is unknown.

Objectives

To describe the scope of the COVID-19 vaccination rollout among US veterans, and to estimate mRNA COVID-19 vaccine effectiveness (VE) as measured by rates of SARS-CoV-2 infection.

Design, setting, and participants

This matched test-negative case-control study was conducted using SARS-CoV-2 test results at Veterans Health Administration sites from December 14, 2020, to March 14, 2021. Vaccine coverage was estimated for all veterans. VE against SARS-CoV-2 infection and COVID-19-related hospitalization and death were estimated using electronic health records from veterans who routinely sought care at a VHA facility and had a test result positive for SA

SUBMITTER: Young-Xu Y 

PROVIDER: S-EPMC8495523 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature