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Integrase Inhibitor Prescribing Disparities in the DC and Johns Hopkins HIV Cohorts.


ABSTRACT: Integrase inhibitors (INSTIs) are recommended by expert panels as initial therapy for people with HIV. Because there can be disparities in prescribing and uptake of novel and/or recommended therapies, this analysis assessed potential INSTI prescribing disparities using a combined data set from the Johns Hopkins HIV Clinical Cohort and the DC Cohort. We performed multivariable logistic regression to identify factors associated with ever being prescribed an INSTI. Disparities were noted, including clinic location, age, and being transgender. Identifying disparities may allow clinicians to focus their attention on these individuals and ensure that therapy decisions are grounded in valid clinical reasons.

SUBMITTER: Monroe AK 

PROVIDER: S-EPMC8496514 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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Integrase Inhibitor Prescribing Disparities in the DC and Johns Hopkins HIV Cohorts.

Monroe Anne K AK   Levy Matthew E ME   Greenberg Alan E AE   Keruly Jeanne C JC   Moore Richard D RD   Horberg Michael A MA   Kulie Paige P   Mohanraj Bernadine S BS   Kumar Princy N PN   Castel Amanda D AD  

Open forum infectious diseases 20210727 8


Integrase inhibitors (INSTIs) are recommended by expert panels as initial therapy for people with HIV. Because there can be disparities in prescribing and uptake of novel and/or recommended therapies, this analysis assessed potential INSTI prescribing disparities using a combined data set from the Johns Hopkins HIV Clinical Cohort and the DC Cohort. We performed multivariable logistic regression to identify factors associated with ever being prescribed an INSTI. Disparities were noted, including  ...[more]

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