Dietary intake and biomarkers of alpha linolenic acid and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of cohort studies.

ABSTRACT:

Objective

To examine the associations between dietary intake and tissue biomarkers of alpha linolenic acid (ALA) and risk of mortality from all causes, cardiovascular disease (CVD), and cancer.

Design

Systematic review and meta-analysis of prospective cohort studies.

Data sources

PubMed, Scopus, ISI Web of Science, and Google Scholar to 30 April 2021.

Study selection

Prospective cohort studies that reported the risk estimates for death from all causes, CVD, and cancer.

Data synthesis

Summary relative risks and 95% confidence intervals were calculated for the highest versus lowest categories of ALA intake using random effects and fixed effects models. Linear and non-linear dose-response analyses were conducted to assess the dose-response associations betw

SUBMITTER: Naghshi S 

PROVIDER: S-EPMC8513503 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature