Ontology highlight
ABSTRACT:
SUBMITTER: Marincin KA
PROVIDER: S-EPMC8516316 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Marincin Kenneth A KA Pal Indrani I Frueh Dominique P DP
Magnetic resonance (Gottingen, Germany) 20210621
Isotope filtering methods are instrumental in biomolecular nuclear magnetic resonance (NMR) studies as they isolate signals of chemical moieties of interest within complex molecular assemblies. However, isotope filters suppress undesired signals of isotopically enriched molecules through scalar couplings, and variations in scalar couplings lead to imperfect suppressions, as occurs for aliphatic and aromatic moieties in proteins. Here, we show that signals that have escaped traditional filters ca ...[more]