Very Low Vitamin D Levels are a Strong Independent Predictor of Mortality in Hospitalized Patients with Severe COVID-19.

ABSTRACT:

Background

There is controversy regarding the association between hypovitaminosis D and COVID-19 outcomes.

Aim of the study

We assessed the association between 25-hydroxyvitamin D levels and COVID-19 outcomes in hospitalized subjects with severe SARS-CoV-2 infection.

Methods

Retrospective cohort study. Serum 25-hydroxyvitamin D levels of subjects with severe COVID-19 pneumonia were measured at hospital admission, between March 17^th, 2020, and March 1^st, 2021.

Results

Out of 2,908 patients, 571 (19.6%) had vitamin D deficiency (defined as a serum 25-hydroxyvitamin D level <12.5 ng/mL [<31.25 nmol/L]), and 1069 (36.7%) had levels between 12.5 ng/mL (31.25 nmol/L) and 20 ng/mL 850 nmol/L). Compared to subjects without vitamin D deficiency, th

SUBMITTER: Ramirez-Sandoval JC 

PROVIDER: S-EPMC8516726 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature