Cognitive dysfunction in young subjects with periodontal disease.

ABSTRACT:

Background

Periodontal disease is an inflammatory, dysbiotic condition. Studies have shown that in the elderly, periodontal disease was associated with cognitive dysfunction and Alzheimer's disease.

Objective

To investigate whether young healthy subjects with periodontal disease have lower cognition compared to those without periodontal disease. The salivary cytokines (IL-1β, TNF-α) levels in relation to cognition were also tested.

Methods

In a monocenter, cross-sectional study, forty subjects [mean age (SD) = 34 (5) and 48% female] from western Romania were classified into periodontal disease conditions using radiographic assessment: 10 subjects had aggressive periodontitis (AGG_P), 20 chronic mild-moderate periodontitis (CR_P), and 10 no periodontitis (NL_P). Neurop

SUBMITTER: Hategan SI 

PROVIDER: S-EPMC8519837 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature