Modified effect of active or passive smoking on the association between age and abdominal aortic calcification: a nationally representative cross-sectional study.

ABSTRACT:

Objective

The deleterious effects of smoking on atherosclerosis were well known; however, the interaction among ageing, smoking and atherosclerosis remains unclear. This study tested the hypothesis that the association between age and vascular calcification, a critical mark of atherosclerosis, was modified by smoking.

Design

Cross-sectional study.

Setting

A nationally representative sample, the National Health and Nutrition Examination Surveys 2013-2014.

Participants

This study included 3140 adults aged 40-80 years with eligible data for abdominal aortic calcification (AAC). Active and passive smoking exposure was identified through self-reports and tobacco metabolites (serum cotinine and urinary 4-methylnitrosamino-3-pyridyl-1-butanol).

Primary outcome measu

SUBMITTER: Lv L 

PROVIDER: S-EPMC8520594 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature