A Longitudinal Study of Resting-State Connectivity and Response to Psychostimulant Treatment in ADHD.

ABSTRACT:

Objective

Psychostimulants are first-line pharmacological treatments for attention deficit hyperactivity disorder (ADHD), although symptom reduction varies widely between patients and these individual differences in treatment response are poorly understood. The authors sought to examine whether the resting-state functional connectivity within and between cingulo-opercular, striato-thalamic, and default mode networks was associated with treatment response to psychostimulant medication, and whether this relationship changed with development.

Methods

Patients with ADHD (N=110; 196 observations; mean age at first observation, 10.83 years, SD=2.2) and typically developing control subjects (N=142; 330 observations; mean age at first observation, 10.49 years, SD=2.81) underwent fun

SUBMITTER: Norman LJ 

PROVIDER: S-EPMC8528221 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature