Aquaporin-Incorporated Graphene-Oxide Membrane for Pressurized Desalination with Superior Integrity Enabled by Molecular Recognition.

ABSTRACT: Aquaporins (AQPs), the natural water channel, have been actively investigated for overcoming the limitations of conventional desalination membranes. An AQP-based biomimetic high-pressure desalination membrane is designed by tethering AQP-carrying red blood cell membrane (RBCM) vesicles onto graphene oxide (GO). RBCMs with AQPs are incorporated into GO based on the molecular recognition between the integrin of RBCM and Arginine-Glycine-Aspartate (RGD) ligand on the GO surface. GO is pre-functionalized with the Glycine-Arginine-Glycine-Aspartate-Serine peptide to capture RBCMs. RBCMs are inserted between GO flakes through the material-specific interaction between integrin of RBCM and RGD ligand, thus ensuring sufficient coverage of channels/defects in the GO for the full functioning of the A

SUBMITTER: Lee CS 

PROVIDER: S-EPMC8529452 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature